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    From an feature in Izvestia

Succinic acid is a natural antioxidant i.e. compound hindering the process of oxidization.
The natural amber, when pulverized, worked just fine against the effects of a hangover whereas the synthesized succinic acids caused no effect whatsoever.
“We found out that the molecules of succinic acid could vary in terms of a spatial structure. The study showed that its conformers had different chemical and biological characteristics. Those findings enabled us to carry out the synthesis of succinic acid with specified characteristics which are similar to those of the natural amber,” said Evgeny Maevski, B.D., in the interview to Izvestia.
The researchers boosted the characteristics of the remedy by adding three more acids into its composition: fumaric, glutamic and ascorbic. All the above are potent antioxidants. Together they are capable of protecting liver and central nervous system from the destructive effects of alcohol. A new preparation was tested in the Research Institute of Narcology under the Ministry of Public Health of Russia.
“We ran tests on the lab animals first, then on the volunteers. The test results showed that the preparation could reduce the toxicity of ethyl alcohol,” says Vladimir Nuzhny, M.D., chief of laboratory of toxicology of the above institute. “It inhibits the production rate of acetic aldehyde, the main poison of alcohol. Besides, it destroys the protons of hydrogen. Too many of them when oxidizing in a human organism bring about the hangover effects, such as headache, nausea etc. Thus the overall aftereffects of the alcoholic intoxication are curtailed. The remedy produces the maximum effect when taken prior to alcohol consumption or in the process of drinking.  

Malushev Igor Urievich
Head of Adaptation Biology and Medicine Department at the Institute of General Pathology and Pathophysiology RAMN, Doctor of Medical Sciences, Professor.

Ogurtsov Pavel Petrovich
Chair of Facultative Therapy at the Russian University, Head of the Somatic Narcology Rehabilitation Department at the National Scientific Narcology Center of Health Ministry of Russia, Doctor of Medical Sciences.

Efremov Alexander Pavlovich
Professor, Doctor of Medical Sciences, Leading specialist at the Russian Scientific Research Institute of Herbs and Aromatic Plants (VILAR).

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